Sanofi dengue vaccine was supposed to be a blockbuster; now, it’s the focus of a scandal

first_img STAT+ is STAT’s premium subscription service for in-depth biotech, pharma, policy, and life science coverage and analysis. Our award-winning team covers news on Wall Street, policy developments in Washington, early science breakthroughs and clinical trial results, and health care disruption in Silicon Valley and beyond. [email protected] An effort by Sanofi to transform its dengue vaccine into a blockbuster product has, instead, turned into a scandal for the drug maker and a public health crisis in the Philippines, where the government is investigating why the vaccine was so widely adopted, despite studies suggesting its use would not be appropriate for everyone.The issue erupted last week when the company disclosed that a new analysis found its Dengvaxia vaccine could actually make future cases of the mosquito-borne virus more severe in people who were not previously infected. And so, Sanofi changed the product labeling to limit use to people who were not exposed to Dengue in the past. Pharmalot Columnist, Senior Writer Ed covers the pharmaceutical industry. GET STARTED By Ed Silverman Dec. 4, 2017 Reprints Ed Silverman Sanofi dengue vaccine was supposed to be a blockbuster; now, it’s the focus of a scandal What’s included? Log In | Learn More center_img What is it? Unlock this article — plus daily coverage and analysis of the pharma industry — by subscribing to STAT+. First 30 days free. GET STARTED Pharmalot Herman Lumanog/Pacific Press/Sipa via AP Daily reporting and analysis The most comprehensive industry coverage from a powerhouse team of reporters Subscriber-only newsletters Daily newsletters to brief you on the most important industry news of the day STAT+ Conversations Weekly opportunities to engage with our reporters and leading industry experts in live video conversations Exclusive industry events Premium access to subscriber-only networking events around the country The best reporters in the industry The most trusted and well-connected newsroom in the health care industry And much more Exclusive interviews with industry leaders, profiles, and premium tools, like our CRISPR Trackr. About the Author Reprints Tags pharmaceuticalsSTAT+Vaccines @Pharmalot last_img read more